Computational Methods in Protein Evolution

Tobias Sikosek Taal: Engels

Gebonden

€ 194,30

Afwijkende levertijd: 46-48 werkdagen
Computational Methods in Protein Evolution

Gebonden

€ 194,30

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This volume presents a diverse collection of methodologies used to study various problems at the protein sequence and structure level. The chapters in this book look at issues ranging from broad concepts like protein space to specifics like antibody modeling. Topics include point mutations, gene duplication, de novo emergence of new genes, pairwise correlated mutations, ancestral protein reconstruction, homology modelling, protein stability and dynamics, and protein-protein interactions. The book also covers a wide range of computational approaches, including sequence and structure alignments, phylogenies, physics-based and mathematical approaches, machine learning, and more. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and prerequisites, step-by-step, readily reproducible computational protocols (using command line or graphical user interfaces, sometimes including computer code), and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Computational Methods in Protein Evolution is a valuable resource that offers useful workflows and techniques that will help both novice and expert researchers working with proteins computationally.<>
ISBN
9781493987351
Vorm
Gebonden
Uitgever
Humana Press Inc.
Druk
1e
Verschenen
01-01-2018
Taal
Engels
Pagina's
420 pp.
Genre
Literaire fictie
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